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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1873986Generated: November 1, 2026

Perchloric Acid → Palonosetron hydrochloride

https://huagongshe.com/reaction/1873986

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPerchloric AcidHCID 24247—
ReactantHCID 6101833HCID 6101833—
SolventAcetic AcidHCID 176—
ProductPalonosetron hydrochlorideHCID 6918303—

Reaction Steps

Palonosetron hydrochloride was prepared from 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one of formula-H using acetic acid and perchloric acid as reaction solvent

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08304544B2
Source datasetuspto-grants-2012_11
ORD IDord-62c191e8564a4c989d2c6549676855a8
Source noteuspto-grants-2012_11