Ammonium Chloride → HCID 67527498, compound

HRID 1873988Notes

Reaction equation

HRID 1873988 reaction equation
[N:1]1([CH2:7][C:8]2[CH:9]=[CH:10][C:11]([N+:18]([O-])=O)=[C:12]([CH:17]=2)[C:13]([O:15][CH3:16])=[O:14])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Cl-].[NH4+]>[Fe].C(O)C.O>[NH2:18][C:11]1[CH:10]=[CH:9][C:8]([CH2:7][N:1]2[CH2:2][CH2:3][O:4][CH2:5][CH2:6]2)=[CH:17][C:12]=1[C:13]([O:15][CH3:16])=[O:14]

Participants

5

Reactant 2

HCID 25517Ammonium ChlorideHCID 67528246HCID 67528246, compound

Product 1

HCID 67527498HCID 67527498, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 19096565Water ethanolSolvent

Procedure

Methyl 5-(morpholin-4-ylmethyl)-2-nitrobenzoate was allowed to undergo a reaction with iron and ammonium chloride in an ethanol-water mixed solvent to obtain methyl 2-amino-5-(morpholin-4-ylmethyl)benzoate.

Sources & evidence

ORD record
ord-d1d88bfd0b224a88a47762884e3a7c09
Source dataset
uspto-grants-2012_11
Patent number
US08304547B2

Reaction notes

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