tert-Butyl carbazate → HCID 67159661, compound

HRID 1874082Notes

Reaction equation

HRID 1874082 reaction equation
[CH2:1]1[CH:3]([CH:4](O)C#N)[CH2:2]1.[C:8]([O:12][C:13](=[O:16])[NH:14][NH2:15])([CH3:11])([CH3:10])[CH3:9]>CO>[C:8]([O:12][C:13]([NH:14][N:15]=[CH:4][CH:3]1[CH2:2][CH2:1]1)=[O:16])([CH3:11])([CH3:10])[CH3:9]

Participants

4

Reactant 2

HCID 70091tert-Butyl carbazateHCID 113893592-Cyclopropyl-2-hydroxyacetonitrile

Product 1

HCID 67159661HCID 67159661, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Cyclopropylcarboxaldehyde (4.07 mL, 14.3 mmol) is dissolved in 3 mL MeOH and tert-butylcarbazate (1.89 g, 14.3 mmol) is added. The reaction mixture is stirred overnight at RT and subsequently concentrated in vacuo. Yield: 2.57 g.

Workup

  1. concentrationsubsequently concentrated in vacuo

Sources & evidence

ORD record
ord-91b69c770b414e77b1c0bda271a27ff0
Source dataset
uspto-grants-2012_11
Patent number
US08304556B2

Reaction notes

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