HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 57749089, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2,5-Dimethyl-2H-pyrazole-3-carbonyl chloride | HCID 2736299 | — |
| Reactant | HCID 57749149 | HCID 57749149 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 57749089 | HCID 57749089 | 10% |
Reaction Steps
In the same manner as in Reference Example 3 and using 5-(3-amino-4-chlorophenoxy)pyridin-2-amine (2.01 g, 8.55 mmol), pyridine (725 μL, 8.98 mmol), 1,3-dimethyl-1H-pyrazole-5-carbonyl chloride (1.42 g, 8.98 mmol) and tetrahydrofuran (50 mL) as starting materials, the title compound (306 mg, 10%) was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304557B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-ff074694484f45d5837a9cdaa714ad59 |
| Source note | uspto-grants-2012_11 |