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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1874459Generated: October 30, 2026

HCID 57749407, compound → N-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

https://huagongshe.com/reaction/1874459

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57749407HCID 57749407—
SolventTrifluoroacetic acidHCID 6422—
ProductN-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamideHCID 5774940189%

Reaction Steps

In the same manner as in Example 29 and using tert-butyl [5-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-2-methylphenyl]carbamate (3.78 g, 8.48 mmol) and trifluoroacetic acid (20 mL) as starting materials, the title compound (2.43 g, 89%) was obtained as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08304557B2
Source datasetuspto-grants-2012_11
ORD IDord-f6a279f9f3684eb89e6c0f0acc2b784e
Source noteuspto-grants-2012_11