HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57749407, compound → N-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57749407 | HCID 57749407 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | N-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide | HCID 57749401 | 89% |
Reaction Steps
In the same manner as in Example 29 and using tert-butyl [5-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-2-methylphenyl]carbamate (3.78 g, 8.48 mmol) and trifluoroacetic acid (20 mL) as starting materials, the title compound (2.43 g, 89%) was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304557B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-f6a279f9f3684eb89e6c0f0acc2b784e |
| Source note | uspto-grants-2012_11 |