Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1875215Generated: November 2, 2026

HCID 178509940, compound → HCID 178509939, compound

https://huagongshe.com/reaction/1875215

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178509940HCID 178509940—
CatalystManganese dioxideHCID 14801—
SolventDichloromethaneHCID 6344—
ProductHCID 178509939HCID 178509939—

Reaction Steps

A solution of N-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}methyl)-4-(hydroxymethyl)-1H-imidazole-2-carboxamide (0.40 g, 0.92 mmol) and MnO2 (0.80 g, 9.2 mmol) in CH2Cl2 (10 mL) was stirred at RT for 2 h. The solution was filtered through celite and evaporated to provide the crude title compound which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08304419B2
Source datasetuspto-grants-2012_11
ORD IDord-ecd6cf4fca3b4099a291a570f6bfda1c
Source noteuspto-grants-2012_11