(-)-Menthol → Menthol

HRID 1875289Notes

Reaction equation

[CH3:1][C@H:2]1[CH2:7][C@@H:6]([OH:8])[C@H:5]([CH:9]([CH3:11])[CH3:10])[CH2:4][CH2:3]1.O[C@@H](C)CC(OC1(C)CCC(C(C)C)CC1)=O>>[CH:2]1([CH3:1])[CH2:3][CH2:4][CH:5]([CH:9]([CH3:10])[CH3:11])[CH:6]([OH:8])[CH2:7]1

Participants

Reactant 2

HCID 16666(-)-Menthol2×

HCID 86648102HCID 86648102, compound

Product 1

HCID 1254Menthol

Procedure

A sensate composition was prepared by mixing 1-menthol and the (3S)-1-menthyl 3-hydroxybutyrate obtained in Example 1 at a ratio of 95:5 (weight ratio). Oral sensory evaluation was carried out by preparing 1,000 ml of a 20 ppm aqueous solution of the thus obtained sensate composition, and the oral sensory evaluation was carried out also on a 20 ppm aqueous solution of 1-menthol alone as a comparison.

Workup

customA sensate composition was prepared
customOral sensory evaluation was carried out by preparing 1,000 ml of a 20 ppm aqueous solution of the thus obtained sensate composition

Sources & evidence

ORD record: ord-353e06def0404811ac8de4cecfb6156c
Source dataset: uspto-grants-2012_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08309062B2

Reaction notes

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