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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1875337Generated: October 30, 2026

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) → HCID 68590100, compound

https://huagongshe.com/reaction/1875337

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
ReactantHCID 58893836HCID 58893836—
ReactantHCID 68590734HCID 68590734—
ProductHCID 68590100HCID 68590100—

Reaction Steps

Prepared analogously to Example 1b from (3SR,4SR)-3-[(5-chloro-thiophene-2-carbonyl)-amino]-4-methoxy-pyrrolidine and (RS)-4,5-dimethyl-4,5,6,7-tetrahydro-thiazolo[5.4-c]pyridine-2-carboxylic acid (prepared analogously to WO2004058728) with HATU as coupling reagent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309542B2
Source datasetuspto-grants-2012_11
ORD IDord-d58a43061edf42ecbf097573183d4466
Source noteuspto-grants-2012_11