Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | HCID 68588340 | HCID 68588340 | — |
| Product | HCID 86761675 | HCID 86761675 | — |
Reaction Steps
1.0 g (4.0 mmol) benzyl 5-oxo-[1,4]diazepine-1-carboxylate are suspended in 1.0 ml (10.6 mmol) dimethylsulphate, stirred for two hours at 90° C. and after cooling dissolved in 10 ml (20 mmol) ammonia solution (2N in methanol). The mixture is stirred for 3.5 hours at RT and then evaporated to dryness.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08309542B2 |
|---|
| Source dataset | uspto-grants-2012_11 |
|---|
| ORD ID | ord-945dbb7ee2c84bc4a92c8207f1607225 |
|---|
| Source note | uspto-grants-2012_11 |
|---|
