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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1875568Generated: October 26, 2026

2,4-Difluorobenzoyl chloride → 2,4-difluorophenyl(3-(2,4-difluorophenyl)-5,6-dihydroimidazo[1,5-a]pyrazin-7(8H)-yl)methanone

https://huagongshe.com/reaction/1875568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluorobenzoyl chlorideHCID 588081—
Reactant3-(2,4-Difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-A]pyrazineHCID 34176318—
Product2,4-difluorophenyl(3-(2,4-difluorophenyl)-5,6-dihydroimidazo[1,5-a]pyrazin-7(8H)-yl)methanoneHCID 44426963—

Reaction Steps

This compound 2 was prepared as described for Example 1 (Step H) starting from 50 mg of 3-(2,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine (Step D) and 2,4-difluorobenzoyl chloride. Yield: 14 mgs, [M+H]+ 376.18.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309571B2
Source datasetuspto-grants-2012_11
ORD IDord-bac43782a43b4a73a6be9e97c361cb4a
Source noteuspto-grants-2012_11