HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyclopropanemethanol → 1-Cyclohexylmethyl-2-(2-cyclopropylmethoxy-pyridin-3-yl)-5,6-difluoro-1H-benzoimidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyclopropanemethanol | HCID 75644 | — |
| Edukt | 2-(2-chloro-pyridin-3-yl)-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole | HCID 86652286 | — |
| Produkt | 1-Cyclohexylmethyl-2-(2-cyclopropylmethoxy-pyridin-3-yl)-5,6-difluoro-1H-benzoimidazole | HCID 51042486 | — |
Reaktionsschritte
The title compound was prepared in analogy to Example 1, from 2-(2-chloro-pyridin-3-yl)-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole (Example 1, intermediate a) and cyclopropyl-methanol (CAS Reg. No. 2516-33-8). Colorless semi-solid (16%). MS (Turbo Spray): m/z=398.3 (M+H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08309581B2 |
| Quelldatensatz | uspto-grants-2012_11 |
| ORD ID | ord-5cd17eed07e547ec8719d654ebb1c275 |
| Quellennotiz | uspto-grants-2012_11 |