HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 51042485, compound → 3-{4-[5,6-Difluoro-2-(2-hydroxy-pyridin-3-yl)-benzoimidazol-1-ylmethyl]-phenyl}-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 51042485 | HCID 51042485 | — |
| Reactant | 3-(4-{5,6-Difluoro-2-[2-(4-methoxy-benzyloxy)-pyridin-3-yl]-benzoimidazol-1-ylmethyl}-phenyl)-propionic acid methyl ester | HCID 67050035 | — |
| Product | 3-{4-[5,6-Difluoro-2-(2-hydroxy-pyridin-3-yl)-benzoimidazol-1-ylmethyl]-phenyl}-propionic acid methyl ester | HCID 178499870 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 5, intermediate b, from 3-(4-{5,6-difluoro-2-[2-(4-methoxy-benzyloxy)-pyridin-3-yl]-benzoimidazol-1-ylmethyl}-phenyl)-propionic acid methyl ester. Colorless solid (69%). MS (Turbo Spray): m/z=424.3 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309581B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-3fa044a454074256bc538fbe0fa520e0 |
| Source note | uspto-grants-2012_11 |