HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Bromomethyl)cyclopentane → 3-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Bromomethyl)cyclopentane | HCID 12723264 | — |
| Reactant | 3-[2-(4-Chloro-2-hydroxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-benzonitrile | HCID 136378499 | — |
| Product | 3-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-benzonitrile | HCID 67050451 | — |
Reaction Steps
The title compound was prepared in analogy to Example 19, from 3-[2-(4-chloro-2-hydroxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-benzonitrile and bromomethyl-cyclopentane (CAS Reg. No. 3814-30-0). Brown solid (33%). MS (Turbo Spray): m/z=378.2 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309581B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-9206c35ac4e44755b6358ac5cdfc4856 |
| Source note | uspto-grants-2012_11 |