HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Bromophenyl)-1H-benzimidazole → 2-(2-bromo-phenyl)-1-cyclohexylmethyl-1H-benzoimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Bromophenyl)-1H-benzimidazole | HCID 97511 | — |
| Reactant | Cyclohexane, (bromomethyl)- | HCID 137636 | — |
| Reactant | 3-{4-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-phenyl}-propionic acid | HCID 58209258 | — |
| Product | 2-(2-bromo-phenyl)-1-cyclohexylmethyl-1H-benzoimidazole | HCID 67050067 | — |
Reaction Steps
The title compound was prepared in analogy to Example 19, intermediate b, from 2-(2-bromo-phenyl)-1H-benzoimidazole and bromomethyl-cyclohexane (CAS Reg. No. 2550-36-9). Light brown solid (62%). MS (Turbo Spray): m/z=369.4 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309581B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-c910f832dbb94d4b921d950ee6a8c045 |
| Source note | uspto-grants-2012_11 |