3-Fluoro-4-methoxyaniline → N-(3-Fluoro-4-methoxyphenyl)-2-methylquinazolin-4-amine

Participants

Reaction Steps

The title compound was prepared from 4-chloro-2-methyl-quinazoline (150 mg, 0.84 mmol), 3-fluoro-4-methoxy-phenylamine (1 18.5 mg, 0.84 mmol) by a procedure similar to Example 78. 1H NMR (CDCl3): 7.89-7.75 (m, 4H), 7.53-7.48 (m, 1H)), 7.38-7.34 (m, 2H), 7.0 (t, J=8.7 Hz, 1H), 3.92 (s, 3H), 2.71 (s, 3H).

Provenance & Evidence