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HRID1876119

反应详情

EQUATION

反应方程式

HRID 1876119 的结构方程式

REACTANTS

反应物

2
结构：CI
HCID6328

Methyl iodide

CH3I

结构：COc1cc(OC)c(Nc2nc(C)nc3ccccc23)c(OC)c1
HCID57938802

2-Methyl-N-(2,4,6-trimethoxyphenyl)quinazolin-4-amine

C18H19N3O3

PRODUCTS

生成物

1
结构：COc1cc(OC)c(N(C)c2nc(C)nc3ccccc23)c(OC)c1
HCID11198562

4-Quinazolinamine, N,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-

C19H21N3O3

PROCEDURE

实验过程

The title compound was prepared from (2-methyl-quinazolin-4-yl)-(2,4,6-trimethoxy-phenyl)-amine (56 mg, 0.17 mmol) and methyl iodide (0.1 ml, 1.6 mmol) by a procedure similar to Example 36. 1H NMR (CDCl3): 7.70 (d, J=8.4 Hz, 1H), 7.49 (t, J=7.8 Hz, 1H), 7.09 (d, J=8.7 Hz, 1H), 6.93 (t, J=8.1 Hz, 1H), 6.18 (s, 2H), 3.86 (s, 3H), 3.63 (s, 6H), 3.44 (s, 3H), 2.70 (s, 3H).