HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 4-Quinazolinamine, N,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 2-Methyl-N-(2,4,6-trimethoxyphenyl)quinazolin-4-amine | HCID 57938802 | — |
| Product | 4-Quinazolinamine, N,2-dimethyl-N-(2,4,6-trimethoxyphenyl)- | HCID 11198562 | — |
Reaction Steps
The title compound was prepared from (2-methyl-quinazolin-4-yl)-(2,4,6-trimethoxy-phenyl)-amine (56 mg, 0.17 mmol) and methyl iodide (0.1 ml, 1.6 mmol) by a procedure similar to Example 36. 1H NMR (CDCl3): 7.70 (d, J=8.4 Hz, 1H), 7.49 (t, J=7.8 Hz, 1H), 7.09 (d, J=8.7 Hz, 1H), 6.93 (t, J=8.1 Hz, 1H), 6.18 (s, 2H), 3.86 (s, 3H), 3.63 (s, 6H), 3.44 (s, 3H), 2.70 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309562B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-c14f4ac463724b99a0aa4fd2cded1aa4 |
| Source note | uspto-grants-2012_11 |