4-Ethoxyaniline → 2-Chloro-N-(4-ethoxyphenyl)quinazolin-4-amine

Participants

Role	Name	HCID	Charge
Reactant	4-Ethoxyaniline	HCID 9076	—
Reactant	2,4-Dichloroquinazoline	HCID 252886	—
Product	2-Chloro-N-(4-ethoxyphenyl)quinazolin-4-amine	HCID 22692729	—

Reaction Steps

The title compound was prepared from 2,4-dichloroquinazoline and 4-ethoxyaniline by a procedure similar to Example 28 (32%). 1H NMR (CDCl3): 7.81 (m, 1H), 7.65 (m, 1H), 7.32 (m, 2H), 7.03 (m, 1H), 6.73 (m, 3H), 4.09 (q, J=7.2, 2H), 1.49 (t, J=7.2, 3H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08309562B2
Source dataset	uspto-grants-2012_11
ORD ID	ord-bd539cf5299b459ab3aea2824723214b
Source note	uspto-grants-2012_11