HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 57938791, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | (2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methylamine | HCID 11558497 | — |
| Product | HCID 57938791 | HCID 57938791 | — |
Reaction Steps
The title compound was prepared from (2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methyl-amine (69 mg, 0.23 mmol) and 2.0 M dimethylamine in methanol (4 ml, 8 mmol) by a procedure similar to Example 122 (51%). 1H NMR (CDCl3): 8.02 (d, J=2.7 Hz, 1H), 7.47 (d, J=8.1 Hz, 1H), 7.38-7.34 (m, 2H), 6.93 (d, J=8.4 Hz, 1H), 6.75-6.66 (m, 2H), 3.94 (s, 3H), 3.51 (s, 3H), 3.30 (s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309562B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-44c63c768a7d43c4bbb4fa2676ce4c50 |
| Source note | uspto-grants-2012_11 |