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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1876139Generated: November 2, 2026

Dimethylamine → HCID 57938791, compound

https://huagongshe.com/reaction/1876139

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
ReactantMethanolHCID 887—
Reactant(2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methylamineHCID 11558497—
ProductHCID 57938791HCID 57938791—

Reaction Steps

The title compound was prepared from (2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methyl-amine (69 mg, 0.23 mmol) and 2.0 M dimethylamine in methanol (4 ml, 8 mmol) by a procedure similar to Example 122 (51%). 1H NMR (CDCl3): 8.02 (d, J=2.7 Hz, 1H), 7.47 (d, J=8.1 Hz, 1H), 7.38-7.34 (m, 2H), 6.93 (d, J=8.4 Hz, 1H), 6.75-6.66 (m, 2H), 3.94 (s, 3H), 3.51 (s, 3H), 3.30 (s, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309562B2
Source datasetuspto-grants-2012_11
ORD IDord-44c63c768a7d43c4bbb4fa2676ce4c50
Source noteuspto-grants-2012_11