HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Isopropoxy-N-methylaniline → (4-Isopropoxy-phenyl)-methyl-(2-methyl-6-nitro-quinazolin-4-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Isopropoxy-N-methylaniline | HCID 18002910 | — |
| Reactant | 4-Chloro-2-methyl-6-nitroquinazoline | HCID 24903866 | — |
| Product | (4-Isopropoxy-phenyl)-methyl-(2-methyl-6-nitro-quinazolin-4-yl)-amine | HCID 59242034 | — |
Reaction Steps
The title compound was synthesized from 4-chloro-2-methyl-6-nitro-quinazoline and (4-isopropoxy-phenyl)-methyl-amine by a procedure similar to Example 1b. 1H NMR (DMSO-d6) δ 8.5-7.1 (7H), 4.73 (m, 1H), 3.7 (s, 3H), 2.7 (s, 3H), 1.32 (d, 6H); LC-MS (ESI+; 353 ([M+H]+)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309562B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-cf64cfeae171492b88a936ded2555c07 |
| Source note | uspto-grants-2012_11 |