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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1876269Generated: November 1, 2026

2-Hydroxy-2-methylpropanehydrazide → 2-hydroxy-N-[(Z)-(6-methoxy-2-oxo-1-pentylindol-3-ylidene)amino]-2-methylpropanamide

https://huagongshe.com/reaction/1876269

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Hydroxy-2-methylpropanehydrazideHCID 3866132—
Reactant1-Pentyl-6-methoxy-isatinHCID 25194456—
Product2-hydroxy-N-[(Z)-(6-methoxy-2-oxo-1-pentylindol-3-ylidene)amino]-2-methylpropanamideHCID 178446202—

Reaction Steps

The title compound was prepared as a yellow solid, using 1-pentyl-6-methoxy-isatin obtained in Example 39(A) and 2-hydroxy-2-methylpropanohydrazide according to the synthetic method E. NMR (CDCl3): δ 0.91 (t, 3H), 1.36 to 1.39 (m, 4H), 1.59 (s, 6H), 1.87 (m, 3H), 2.63 (s, 1H), 3.68 (t, 2H), 3.87 (s, 3H), 6.41 (d, 1H), 6.61 (dd, 1H), 7.73 (d, 1H), 13.71 (br s, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309595B2
Source datasetuspto-grants-2012_11
ORD IDord-1f85ab287eda43cdb0c2f5adfcd94a23
Source noteuspto-grants-2012_11