Water → HCID 13078526, compound

HRID 1876306Notes

Reaction equation

HRID 1876306 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[CH3:11][S:12][C:13]1[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=1.C(=O)([O-])[O-].[K+].[K+].O>CS(C)=O>[CH3:11][S:12][C:13]1[CH:18]=[CH:17][C:16]([O:19][C:2]2[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=2)=[CH:15][CH:14]=1

Participants

6

Reactant 4

HCID 962WaterHCID 74741-Chloro-4-nitrobenzeneHCID 11430Potassium CarbonateHCID 140864-(Methylthio)phenol

Product 1

HCID 13078526HCID 13078526, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
100 °C

Procedure

1-Chloro-4-nitrobenzene (15 g, 95 mmol) and 4-(methylmercapto)phenol (13.3 g, 95 mmol) were dissolved in dimethylsulfoxide (100 ml). Potassium carbonate (15.8 g, 134 mmol) was added thereto, and the mixture was stirred for 12 h at 100° C. After completion of the reaction, excess water was added to give precipitated solid. The solid was filtered, and dried to give 1-(4-methylsulfanylphenoxy)-4-nitrobenzene.

Workup

  1. additionwas added
  2. customto give
  3. customprecipitated solid
  4. filtrationThe solid was filtered
  5. customdried

Sources & evidence

ORD record
ord-fa118d9cf5ae4607a2be4faf940b7dc1
Source dataset
uspto-grants-2012_11
Patent number
US08309586B2

Reaction notes

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