HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 59543027, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | [(R)-2-(5-chloro-7-cyclopentylamino-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]acetic acid | HCID 25196145 | — |
| Product | HCID 59543027 | HCID 59543027 | 87% |
Reaction Steps
The compound (50 mg, 0.13 mmol) prepared in Example 27 and methylamine instead of morpholine were reacted according to the same procedure as Example 73 to give the title compound (45 mg, Yield 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309586B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-f231e5cb90624db7a4b2374c64a8560a |
| Source note | uspto-grants-2012_11 |