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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1876319Generated: November 3, 2026

Methylamine → HCID 59543027, compound

https://huagongshe.com/reaction/1876319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant[(R)-2-(5-chloro-7-cyclopentylamino-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]acetic acidHCID 25196145—
ProductHCID 59543027HCID 5954302787%

Reaction Steps

The compound (50 mg, 0.13 mmol) prepared in Example 27 and methylamine instead of morpholine were reacted according to the same procedure as Example 73 to give the title compound (45 mg, Yield 87%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309586B2
Source datasetuspto-grants-2012_11
ORD IDord-f231e5cb90624db7a4b2374c64a8560a
Source noteuspto-grants-2012_11