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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1876322Generated: October 31, 2026

3-(Dimethylamino)pyrrolidine → HCID 59543030, compound

https://huagongshe.com/reaction/1876322

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Dimethylamino)pyrrolidineHCID 2758519—
Reactant[(R)-2-(5-chloro-7-cyclopentylamino-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]acetic acidHCID 25196145—
ProductHCID 59543030HCID 5954303048%

Reaction Steps

The compound (40 mg, 0.11 mmol) prepared in Example 27 and 3-dimethylaminopyrrolidine instead of morpholine were reacted according to the same procedure as Example 73 to give the title compound (24 mg, Yield 48%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309586B2
Source datasetuspto-grants-2012_11
ORD IDord-4cb80607f8594f2e9b08a763d94ee2c7
Source noteuspto-grants-2012_11