1,4-Dioxane hydrochloride → HCID 59543058, compound

Participants

Reaction Steps

The compound (150 mg, 0.27 mmol) prepared in Example 114 was dissolved in dichloromethane (30 ml). 4N hydrochloric acid dioxane solution (0.34 ml, 1.35 mmol) was added thereto, and the mixture was stirred for 4 h at room temperature. After completion of the reaction, the reaction solution was distilled under reduced pressure to give a solid. The solid was washed with ethylether, and dried to give the title compound (92 mg, Yield 75%).

Provenance & Evidence