反应详情

A mixture of tert-butyl 4-{2-[4-(2-chloro-5-methoxypyrimidin-4-yl)-1H-pyrazol-1-yl]-3-cyanopropyl}piperidine-1-carboxylate (0.030 g, 0.000065 mol) and 0.5 mL of TFA was stirred at room temperature for 1 h. After being evaporated to dryness, the residue was used directly in next step.

1. customAfter being evaporated to dryness