HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-methyl-3-oxopentanoate → Methyl 2-isopropyl-5-[4-(trifluoromethyl)phenyl]-3-furoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-methyl-3-oxopentanoate | HCID 2759969 | — |
| Reactant | 2-Chloro-1-[4-(trifluoromethyl)phenyl]ethan-1-one | HCID 12789977 | — |
| Product | Methyl 2-isopropyl-5-[4-(trifluoromethyl)phenyl]-3-furoate | HCID 23074492 | 36.5% |
Reaction Steps
An operation similar to that in Example 1 (1) was performed using 2-chloro-4′-(trifluoromethyl)acetophenone (13.4 g) and methyl 4-methyl-3-oxopentanoate (7.2 g) to give the title compound (5.7 g, 36%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309580B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-391e3ec9bb9e4646a84e5e958134df10 |
| Source note | uspto-grants-2012_11 |