Thionyl Chloride → HCID 68514191, compound

HRID 1877026Notes

Reaction equation

HRID 1877026 reaction equation
[CH:1]1([CH:7]([C:9]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=3)[O:11][C:10]=2[CH3:20])O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.S(Cl)([Cl:23])=O>C1(C)C=CC=CC=1>[Cl:23][CH:7]([CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[C:9]1[CH:13]=[C:12]([C:14]2[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=2)[O:11][C:10]=1[CH3:20]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 68515304HCID 68515304, compound

Product 1

HCID 68514191HCID 68514191, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a solution of cyclohexyl[2-methyl-5-(pyridin-4-yl)furan-3-yl]methanol (0.9 g) in toluene (10 mL) was added thionyl chloride (0.7 mL), and the mixture was stirred at room temperature overnight. The solvent was evaporated under reduced pressure to give the title compound (0.9 g, 100%) as a yellow crystal.

Workup

  1. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-88a8b347b9b2474394e9b53b1e517b31
Source dataset
uspto-grants-2012_11
Patent number
US08309580B2

Reaction notes

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