Thionyl Chloride → HCID 68511060, compound

HRID 1877049Notes

Reaction equation

HRID 1877049 reaction equation
[CH:1]1([CH:7]([C:9]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[O:11][C:10]=2[CH3:20])O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.S(Cl)([Cl:23])=O>C1(C)C=CC=CC=1>[ClH:23].[Cl:23][CH:7]([CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[C:9]1[CH:13]=[C:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[O:11][C:10]=1[CH3:20]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 68509119HCID 68509119, compound

Product 1

HCID 68511060HCID 68511060, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a solution of cyclohexyl[2-methyl-5-(pyridin-2-yl)furan-3-yl]methanol (0.7 g) in toluene (20 mL) was added thionyl chloride (1.3 mL), and the mixture was stirred at room temperature for 2 hr. The solvent was evaporated under reduced pressure to give the title compound (0.8 g, 100%) as a yellow crystal.

Workup

  1. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-3636d3b4206448ab837005979a778d5e
Source dataset
uspto-grants-2012_11
Patent number
US08309580B2

Reaction notes

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