Thionyl Chloride → HCID 68515580, compound

HRID 1877248Notes

Reaction equation

HRID 1877248 reaction equation
[CH:1]1([CH:7]([C:9]2[S:10][C:11]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:12][C:13]=2[CH3:14])O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.S(Cl)([Cl:23])=O>C1(C)C=CC=CC=1>[Cl:23][CH:7]([CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[C:9]1[S:10][C:11]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:12][C:13]=1[CH3:14]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 68515326HCID 68515326, compound

Product 1

HCID 68515580HCID 68515580, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a solution of cyclohexyl(3-methyl-5-phenylthiophen-2-yl)methanol (0.8 g) in toluene (20 mL) was added thionyl chloride (0.3 mL), and the mixture was stirred at room temperature for 2 hr. The solvent was evaporated under reduced pressure to give the title compound (0.9 g, 100%).

Workup

  1. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-f85d98e9a7ef4c7097e034117e0050aa
Source dataset
uspto-grants-2012_11
Patent number
US08309580B2

Reaction notes

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