HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1877851Generated: November 2, 2026
Potassium Carbonate → N-benzyl-6-chloro-N-(1-methylethyl)pyrazin-2-amine
https://huagongshe.com/reaction/1877851
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Dimethylacetamide | HCID 31374 | — |
| Reactant | Isopropylbenzylamine | HCID 66024 | — |
| Reactant | 2,6-Dichloropyrazine | HCID 78504 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-benzyl-6-chloro-N-(1-methylethyl)pyrazin-2-amine | HCID 61699183 | — |
Reaction Steps
A mixture of 2,6-dichloropyrazine (7.45 g), N-benzylpropan-2-amine (12.5 mL), potassium carbonate (10.4 g) and DMA (50 mL) was stirred at 80° C. for 15 hr. Water (100 mL) was added, and the mixture was extracted with ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08314088B2 |
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| Source dataset | uspto-grants-2012_11 |
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| ORD ID | ord-92af8d12369046aa9789b250a4733aeb |
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| Source note | uspto-grants-2012_11 |
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