m-Chlorophenylhydrazine hydrochloride → HCID 58277354, compound

HRID 1877975Notes

Reaction equation

HRID 1877975 reaction equation
[CH2:1]([O:3][C:4](=[O:21])[C:5](=O)/[CH:6]=[C:7](/[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][C:16]([F:19])([F:18])[F:17])[CH:10]=1)\[O-])[CH3:2].[Li+].Cl.[Cl:24][C:25]1[CH:26]=[C:27]([NH:31][NH2:32])[CH:28]=[CH:29][CH:30]=1>>[Cl:24][C:25]1[CH:26]=[C:27]([N:31]2[C:7]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([O:15][C:16]([F:19])([F:18])[F:17])[CH:10]=3)=[CH:6][C:5]([C:4]([O:3][CH2:1][CH3:2])=[O:21])=[N:32]2)[CH:28]=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 75331m-Chlorophenylhydrazine hydrochlorideHCID 58277340HCID 58277340, compound

Product 1

HCID 58277354HCID 58277354, compoundYield 33%

Procedure

Starting from 4.53 g (14.6 mmol) of lithium (1Z)-4-ethoxy-3,4-dioxo-1-[3-(trifluoro-methoxy)phenyl]but-1-en-1-olate from example 3A and 3.56 g (19.8 mmol) of 3-chloro-phenylhydrazine hydrochloride, 1.98 g (4.8 mmol, 33% yield of theory) of product are obtained according to the method described in example 4A.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-dcd8c8e3dc434cd89a0730c26081502e
Source dataset
uspto-grants-2012_11
Patent number
US08314089B2

Reaction notes

Loading…