HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 68488223, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | HCID 44550274 | HCID 44550274 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68488223 | HCID 68488223 | — |
Reaction Steps
4-Fluoro-N-{[2-oxo-6-(1H-pyrazol-1-yl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-4-yl]methyl}benzamide was subjected to optical resolution by HPLC (Chiralpack AD-H, n-hexane:ethanol=4:1), and a fraction eluted at a later time was concentrated, whereby the objective compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314094B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-e39b8b9761a34352b647510073415f47 |
| Source note | uspto-grants-2012_11 |