化工社化工社 化学情報印刷レポート · 研究参考用
N-(2-Cyanophenyl)piperazine → 1-[(2-Methoxy-6-methylquinoxalin-3-yl)aminocarbonyl]-4-(2-cyanophenyl)piperazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(2-Cyanophenyl)piperazine | HCID 2735875 | — |
| 反応物 | Ethyl N-(2-methoxy-6-methylquinoxalin-3-yl)carbamate | HCID 66917958 | — |
| 生成物 | 1-[(2-Methoxy-6-methylquinoxalin-3-yl)aminocarbonyl]-4-(2-cyanophenyl)piperazine | HCID 66918245 | 91% |
反応手順
Ethyl N-(2-methoxy-6-methylquinoxalin-3-yl)carbamate and 1-(2-cyanophenyl)piperazine were reacted by the same way with the example 43 to obtain the titled compound (yield, 91%). 1H NMR (300 MHz, CDCl3): δ 2.46 (s, 3H), 3.28 (s, 4H), 3.86 (s, 3H), 4.08-4.19 (m, 4H), 7.01-7.08 (m, 3H), 7.17-7.37 (m, 1H), 7.49-7.61 (m, 4H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08314100B2 |
| 出典データセット | uspto-grants-2012_11 |
| ORD ID | ord-8904e34f177d49fba80899dd7bbc6d66 |
| 出典メモ | uspto-grants-2012_11 |