2-Mepp → HCID 69243672, compound

HRID 1878192Notes

Reaction equation

HRID 1878192 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([NH:12][C:13](=[O:17])OCC)[C:6]([O:18][CH3:19])=[N:5]2.[CH3:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([NH:12][C:13]([N:30]1[CH2:31][CH2:32][N:27]([C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=3[CH3:20])[CH2:28][CH2:29]1)=[O:17])[C:6]([O:18][CH3:19])=[N:5]2

Participants

3

Reactant 2

HCID 919652-MeppHCID 69243333ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate

Product 1

HCID 69243672HCID 69243672, compoundYield 77%

Procedure

Ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate and 1-(2-methylphenyl)piperazine were reacted by the same way with the example 85 to obtain the titled compound (yield, 77%). 1H NMR (200 MHz, CDCl3): δ 2.95 (s, 3H), 2.99-3.02 (m, 4H), 3.74-3.77 (m, 4H), 4.15 (s, 3H), 7.01-7.05 (m, 2H), 7.17-7.42 (m, 5H), 7.81-7.84 (m, 1H).

Sources & evidence

ORD record
ord-c024ff12ed7e4169bf9fc664cf63c5c2
Source dataset
uspto-grants-2012_11
Patent number
US08314100B2

Reaction notes

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