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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878205Generated: November 1, 2026

1-(2-Pyrimidinyl)piperazine → HCID 69242587, compound

https://huagongshe.com/reaction/1878205

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyrimidinyl)piperazineHCID 88747—
Reactantethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamateHCID 69243333—
ProductHCID 69242587HCID 6924258779%

Reaction Steps

Ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate and 1-(2-pyrimidyl)piperazine were reacted by the same way with the example 85 to obtain the titled compound (yield, 79%). 1H NMR (200 MHz, CDCl3): δ 3.69 (s, 4H), 3.98 (s, 4H), 4.14 (s, 3H), 6.54 (t, J=4.8 Hz, 1H), 7.21-7.41 (m, 3H), 7.79 (t, J=8.4 Hz, 1H), 8.34 (d, J=4.8 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314100B2
Source datasetuspto-grants-2012_11
ORD IDord-d45f439e69124d6b957e131f0601ba7e
Source noteuspto-grants-2012_11