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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878273Generated: November 2, 2026

1-(2-Pyrimidinyl)piperazine → HCID 69243596, compound

https://huagongshe.com/reaction/1878273

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyrimidinyl)piperazineHCID 88747—
Reactantethyl N-(3,6-dimethoxyquinoxalin-2-yl)carbamateHCID 69244324—
ProductHCID 69243596HCID 6924359686%

Reaction Steps

Ethyl N-(3,6-dimethoxyquinoxalin-2-yl)carbamate and 1-(2-pyrimidyl)piperazine were reacted by the same way with the example 148 to obtain the titled compound (yield, 86%). 1H NMR (300 MHz, CDCl3): δ 3.67-3.70 (m, 4H), 3.90 (s, 3H), 3.95-3.97 (m, 4H), 4.13 (s, 3H), 6.53 (t, J=4.8 Hz, 1H), 7.11-7.23 (m, 4H), 7.30 (d, J=9.3 Hz, 1H), 8.33 (d, J=4.8 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314100B2
Source datasetuspto-grants-2012_11
ORD IDord-6a76c0e51a0044779d9debb68ddfc244
Source noteuspto-grants-2012_11