Hydrochloric Acid → HCID 66878102, compound

Participants

Reaction Steps

(3S,5R)-tert-Butyl 4-(3-(tert-butylcarbamoyl)benzyl)-3,5-dimethylpiperazine-1-carboxylate (0.07 g, 0.17 mmol) was treated with an ethanolic solution of hydrochloric acid (2 mL, 14.5 wt % hydrochloric acid in ethanol). The resultant mixture was stirred at room temperature for 2 hours. The mixture was concentrated under vacuum, azeotroped with dichloromethane (×2) and dried under vacuum to afford the title compound (0.052 g) as a white foamy solid. MS (ESI) m/z 304.4 [M+H]+

Provenance & Evidence