HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 66878628, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl 4-(4-(3-phenylureido)benzoyl)piperazine-1-carboxylate | HCID 46511620 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66878628 | HCID 66878628 | — |
Reaction Steps
tert-Butyl 4-(4-(3-phenylureido)benzoyl)piperazine-1-carboxylate (15.0 g, 35.34 mmol) was stirred with 50% trifluoroacetic acid in dichloromethane (200 ml) at room temperature for 1 hour. The reaction was concentrated under vacuum and then dryed overnight on high vacuum to afford the title compound (15.5 g). MS (ESI) m/z 325.0 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314091B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-c5e7648f60544a63a09a51399439cf83 |
| Source note | uspto-grants-2012_11 |