Morpholine → HCID 58531012, compound

Participants

Reaction Steps

There was dissolved, in 1,4-dioxane (5 mL), 2-(4-bromo-phenyl)-5,7-dichloro-pyrazolo[1,5-a]pyrimidine (217 mg, 0.633 mM), then morpholine (110 μL, 1.27 mM) was added to the solution and the mixture was stirred at room temperature for one hour. The solvent was distilled off from this reaction mixture and the residue thus obtained was diluted with water and then extracted with methylene chloride. The extracts obtained were combined together, dried over anhydrous sodium sulfate, the solvent was distilled off and then the resulting solid was washed with methanol to thus give the title compound (240 mg, yield: 96%).

Provenance & Evidence