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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878565Generated: November 2, 2026

Acetic Acid → HCID 77967092, compound

https://huagongshe.com/reaction/1878565

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantIndole-4-carboxaldehydeHCID 333703—
ReactantHCID 70867226HCID 70867226—
SolventEthanolHCID 702—
ProductHCID 77967092HCID 7796709258%

Reaction Steps

To a solution of 7-morpholin-4-yl-2-phenyl-pyrazolo[1,5-a]pyrimidin-5-yl-hydrazine (15 mg, 0.048 mM) in absolute ethanol (2.0 mL), there were added 4-formyl-indole (11 mg, 0.076 mM) and acetic acid (2.0 μL) and the mixture was stirred at room temperature for 3 hours. The precipitated solid was filtered off and then washed with ethanol to thus give the title compound (12 mg, yield: 58%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314098B2
Source datasetuspto-grants-2012_11
ORD IDord-1915d7d9b07542ada6d4f8d06de0a891
Source noteuspto-grants-2012_11