HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Pyridin-3-yl-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine → 2-(6-Methyl-pyridin-2-yl)-4-pyridin-3-yl-7H-pyrrolo[2,3-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Pyridin-3-yl-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine | HCID 68738868 | — |
| Reactant | 4-Chloro-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine | HCID 86632427 | — |
| Reactant | 4-chloro-2-(6-methyl-pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidine | HCID 86632428 | — |
| Product | 2-(6-Methyl-pyridin-2-yl)-4-pyridin-3-yl-7H-pyrrolo[2,3-d]pyrimidine | HCID 68935386 | — |
Reaction Steps
2-(6-Methyl-pyridin-2-yl)-4-pyridin-3-yl-7H-pyrrolo[2,3-d]pyrimidine is prepared by an analogous method to 4-pyridin-3-yl-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine (Example 1) by replacing 4-chloro-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine (Intermediate 1) with 4-chloro-2-(6-methyl-pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidine (Intermediate 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314112B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-5b8ea4d36a8a4dad924401310a934bce |
| Source note | uspto-grants-2012_11 |