HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-chloro-6-(6-methyl-pyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine → 6-(6-Methyl-pyridin-2-yl)-4-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-chloro-6-(6-methyl-pyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine | HCID 68790241 | — |
| Reactant | 2-(6-Methyl-pyridin-2-yl)-4-pyridin-3-yl-7H-pyrrolo[2,3-d]pyrimidine | HCID 68935386 | — |
| Reactant | 4-Chloro-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine | HCID 86632427 | — |
| Product | 6-(6-Methyl-pyridin-2-yl)-4-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridine | HCID 68940431 | — |
Reaction Steps
6-(6-Methyl-pyridin-2-yl)-4-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridine is prepared by an analogous method to that for 2-(6-methyl-pyridin-2-yl)-4-pyridin-3-yl-7H-pyrrolo[2,3-d]pyrimidine (Example 2) by replacing 4-chloro-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine (Intermediate 1) with 4-chloro-6-(6-methyl-pyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine (Intermediate 6).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314112B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-c4541ef8d6d74cc79d2eeec8f280f6ea |
| Source note | uspto-grants-2012_11 |