HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67533049, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | HCID 57448049 | HCID 57448049 | — |
| Product | HCID 67533049 | HCID 67533049 | — |
Reaction Steps
Preparation according to Example 29: 4-[2-methoxy-3-(trifluoromethoxy)phenyl]-1-propylpiperidine (1.32 g, 4.16 mmol), pyridine hydrochloride (3 g). Yield: 0.7 g (55%). The amine was converted to the hydrochloric acid salt and recrystallized from ethanol/diethyl ether: M.p. 203-205° C. MS m/z (relative intensity, 70 eV) 303 (M+, 11), 275 (15), 274 (bp), 145 (4), 117 (6).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314126B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-441743e4ca76499c936c5a77500353d0 |
| Source note | uspto-grants-2012_11 |