Iodoethane → HCID 57438797, compound

HRID 1879050Notes

Reaction equation

HRID 1879050 reaction equation
[F:1][C:2]1[C:10]([C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].I[CH2:18][CH3:19].[BH4-].[Na+]>C(O)C>[CH2:18]([N:14]1[CH2:15][CH:16]=[C:11]([C:10]2[C:2]([F:1])=[C:3]([CH:7]=[CH:8][CH:9]=2)[C:4]([NH2:6])=[O:5])[CH2:12][CH2:13]1)[CH3:19]

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 4311764Sodium borohydrideHCID 46315507HCID 46315507, compound

Product 1

HCID 57438797HCID 57438797, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Preparation according to preparation 6: 2-fluoro-3-pyridin-4-ylbenzamide (0.94 g, 4.34 mmol), 1-iodoethane (3 ml), ethanol (40 ml), sodium borohydride (1.25 g, 34.8 mmol). Yield: 0.75 g. MS m/z (rel. intensity, 70 eV) 248 (M+, bp), 247 (37), 233 (99), 146 (22), 110 (41).

Workup

  1. customPreparation
  2. customaccording to preparation 6

Sources & evidence

ORD record
ord-cd93abc90abe49fd94869bee2ed01a7d
Source dataset
uspto-grants-2012_11
Patent number
US08314126B2

Reaction notes

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