HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester 4-thiocarbamoyl benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Trimebutine | HCID 5573 | — |
| Reactant | 4-Carbamothioylbenzoic acid | HCID 16772501 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester 4-thiocarbamoyl benzoate | HCID 86616553 | — |
Reaction Steps
To a mixture of 4-(thiocarbamoyl)benzoic acid (0.1 mol) and trimebutine (0.1 mol), water (200 mL) and ethyl alcohol (20 mL) have been added and the resulting suspension has been stirred at room temperature until clear. Then the solution has been frozen and lyophilized furnishing the desired salt (quantitative yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314140B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-c2bbf2c77d9042dbbd82ebcbd4ba9a51 |
| Source note | uspto-grants-2012_11 |