HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1879596Generated: October 26, 2026
Phosphorus oxychloride → 3-Chloro-5-phenyl-pyridazine-4-carbonitrile
https://huagongshe.com/reaction/1879596
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 3-Oxo-5-phenyl-2,3-dihydro-pyridazine-4-carbonitrile | HCID 59735096 | — |
| Product | 3-Chloro-5-phenyl-pyridazine-4-carbonitrile | HCID 59735097 | — |
Reaction Steps
3-Oxo-5-phenyl-2,3-dihydro-pyridazine-4-carbonitrile (70 mg) was suspended in 1 mL phosphorous oxychloride and heated to 100° C. for 6 hours. The mixture was then cooled and poured onto ice. The resulting brown solid product was filtered and air dried and used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08318467B2 |
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| Source dataset | uspto-grants-2012_11 |
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| ORD ID | ord-800015b3b78a43a9babce63e6add21b0 |
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| Source note | uspto-grants-2012_11 |
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