反应详情

3-Chloro-5-phenyl-pyridazine-4-carbonitrile obtained from Step B was suspended in 1 ml ethanol with 23 μL hydrazine and the mixture was refluxed for several hours. The solvent was then evaporated and the title product was purified by silica gel chromatography (1:9 methanol/dichloromethane): MS (ES+) 212 (M+H); HPLC 1.121 minutes.

1. temperaturethe mixture was refluxed for several hours
2. customThe solvent was then evaporated
3. customthe title product was purified by silica gel chromatography (1:9 methanol/dichloromethane)
4. customHPLC 1.121 minutes