HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → 4-phenyl-1H-pyrazolo[5,4-c]pyridazin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 3-Chloro-5-phenyl-pyridazine-4-carbonitrile | HCID 59735097 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-phenyl-1H-pyrazolo[5,4-c]pyridazin-3-amine | HCID 86588605 | — |
Reaction Steps
3-Chloro-5-phenyl-pyridazine-4-carbonitrile obtained from Step B was suspended in 1 ml ethanol with 23 μL hydrazine and the mixture was refluxed for several hours. The solvent was then evaporated and the title product was purified by silica gel chromatography (1:9 methanol/dichloromethane): MS (ES+) 212 (M+H); HPLC 1.121 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318467B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-a60c7f5a9dae42fe9e9782d65a3b2ebd |
| Source note | uspto-grants-2012_11 |