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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1880312Generated: November 1, 2026

HCID 57471974, compound → HCID 57471975, compound

https://huagongshe.com/reaction/1880312

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57471974HCID 57471974—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 57471975HCID 57471975—

Reaction Steps

A solution of tert-butyl 2-(4-(2-((1R,2S)-2-aminocyclohexylamino)-5-carbamoylpyrimidin-4-ylamino)phenoxy)acetate racemate (180 mg, 0.395 mmol) in TFA (4 mL) was stirred at room temperature for 2 h. It was then concentrated in vacuo. The residue was purified by HPLC to give the titled compound (60 mg). MS 401.2 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318755B2
Source datasetuspto-grants-2012_11
ORD IDord-fea41fa19a4d45498b01b1b2676f78ca
Source noteuspto-grants-2012_11